KMID : 0604520220480020181
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Journal of the Society of Cosmetic Scientists of Korea 2022 Volume.48 No. 2 p.181 ~ p.188
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Structure and Function of Tight Junctions in the Skin
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Song Mee
Baek Ji-Hwoon
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Abstract
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The skin protects the body from excessive water loss and the invasion of harmful substances, such as chemicals and microbes. The stratum corneum, is recognized as a very important physical barrier. However, in recent years evidence emerged that tight junctions (TJ) might also play a crucial role in barrier function of the skin. In the present study, TJ proteins including transmembrane proteins and plaque proteins, skin permeability barrier function and skin diseases of TJ were reviewed.
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KEYWORD
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epidermis, barrier, tight junction
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