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KMID : 0604520220480020181
Journal of the Society of Cosmetic Scientists of Korea
2022 Volume.48 No. 2 p.181 ~ p.188
Structure and Function of Tight Junctions in the Skin
Song Mee

Baek Ji-Hwoon
Abstract
The skin protects the body from excessive water loss and the invasion of harmful substances, such as chemicals and microbes. The stratum corneum, is recognized as a very important physical barrier. However, in recent years evidence emerged that tight junctions (TJ) might also play a crucial role in barrier function of the skin. In the present study, TJ proteins including transmembrane proteins and plaque proteins, skin permeability barrier function and skin diseases of TJ were reviewed.
KEYWORD
epidermis, barrier, tight junction
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